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A simplified up-down method (SUDO) for measuring mechanical nociception in rodents using von Frey filaments

BACKGROUND: The measurement of mechanosensitivity is a key method for the study of pain in animal models. This is often accomplished with the use of von Frey filaments in an up-down testing paradigm. The up-down method described by Chaplan et al. (J Neurosci Methods 53:55–63, 1994) for mechanosensit...

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Bibliographic Details
Main Authors: Bonin, Robert P, Bories, Cyril, De Koninck, Yves
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020614/
https://ncbi.nlm.nih.gov/pubmed/24739328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-26
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