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Genomic organization and sequences of immunoglobulin light chain genes in a primitive vertebrate suggest coevolution of immunoglobulin gene organization.

The genomic organization and sequence of immunoglobulin light chain genes in Heterodontus francisci (horned shark), a phylogenetically primitive vertebrate, have been characterized. Light chain variable (VL) and joining (JI) segments are separated by 380 nucleotides and together with the single cons...

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Bibliographic Details
Published in:EMBO J
Main Authors: Shamblott, M J, Litman, G W
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC402057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2511000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08549.x
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