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Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3' untranslated region of the mRNA.

Post-transcriptional regulation of transferrin receptor mRNA levels by iron is mediated by a portion of the 3' untranslated region (UTR) of the mRNA. We have previously shown that a 678 nucleotide fragment of the 3'UTR contains the regulatory element(s). Within this region are five RNA structures wh...

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Published in:EMBO J
Main Authors: Casey, J L, Koeller, D M, Ramin, V C, Klausner, R D, Harford, J B
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1989
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC402052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583116/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08544.x
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