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The Pla Protease of Yersinia pestis Degrades Fas Ligand to Manipulate Host Cell Death and Inflammation

Pneumonic plague is a deadly respiratory disease caused by Yersinia pestis. The bacterial protease Pla contributes to disease progression and manipulation of host immunity, but the mechanisms by which this occurs are largely unknown. Here we show that Pla degrades the apoptotic signaling molecule Fa...

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Библиографические подробности
Главные авторы: Caulfield, Adam J., Walker, Margaret E., Gielda, Lindsay M., Lathem, Wyndham W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020149/
https://ncbi.nlm.nih.gov/pubmed/24721571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.03.005
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