Two-photon imaging of Zn(2+) dynamics in mossy fiber boutons of adult hippocampal slices

Mossy fiber termini in the hippocampus accumulate Zn(2+), which is released with glutamate from synaptic vesicles upon neural excitation. Understanding the spatiotemporal regulation of mobile Zn(2+) at the synaptic level is challenging owing to the difficulty of visualizing Zn(2+) at individual syna...

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Bibliografiske detaljer
Main Authors: Khan, Mustafa, Goldsmith, Christian R., Huang, Zhen, Georgiou, John, Luyben, Thomas T., Roder, John C., Lippard, Stephen J., Okamoto, Kenichi
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020060/
https://ncbi.nlm.nih.gov/pubmed/24757053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405154111
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