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Statistical issues and challenges in immuno-oncology

BACKGROUND: The development of immuno-oncologic agents poses unique challenges, namely that both efficacy and safety profiles differ from previously characterized cytotoxic and pathway-specific agents. In addition, exponential distribution is usually assumed in study designs with time-to-event endpo...

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Detalhes bibliográficos
Autor principal: Chen, Tai-Tsang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019889/
https://ncbi.nlm.nih.gov/pubmed/24829754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-1426-1-18
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