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Induction of activation-induced cytidine deaminase by a not-directly mutagenic carcinogen: a novel potential molecular mechanism

OBJECTIVE: The molecular mechanisms underlying the carcinogenic activity of not-directly mutagenic (Ames mutagenicity test-negative) carcinogens are not fully understood. Given recent findings that ectopic expression of activation-induced cytidine deaminase (AID) in somatic cells plays a critical ro...

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Detalhes bibliográficos
Main Authors: Tatemichi, Masayuki, Hata, Harumi, Nakadate, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019765/
https://ncbi.nlm.nih.gov/pubmed/24643881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12199-014-0382-x
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