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Repeated Cocaine Treatment Enhances HIV-1 Tat-induced Cortical Excitability via Over-activation of L-type Calcium Channels
The prefrontal cortex (PFC) is dysregulated in neuroAIDS and during cocaine abuse. Repeated cocaine treatment upregulates voltage gated L-type Ca(2+) channels in pyramidal neurons within the rat medial PFC (mPFC). L-type Ca(2+) channels are also upregulated by the HIV-1 neurotoxic protein, Tat, but...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019717/ https://ncbi.nlm.nih.gov/pubmed/24567038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9524-6 |
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