In vivo evidence for β(2) nicotinic acetylcholine receptor subunit upregulation in smokers as compared to nonsmokers with schizophrenia

BACKGROUND: Schizophrenia is associated with very high rates of tobacco smoking. The latter may be related to an attempt to “self-medicate” symptoms and/or to alterations in function of high affinity nicotinic acetylcholine receptors (β(2)(*)-nAChRs). METHODS: Smoking and nonsmoking subjects with sc...

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Main Authors: Esterlis, Irina, Bois, Frederic, Pittman, Brian, Picciotto, Marina R., Shearer, Lara, Anticevic, Alan, Carlson, Jon, Niciu, Marc, Cosgrove, Kelly P., D’Souza, D. Cyril
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019710/
https://ncbi.nlm.nih.gov/pubmed/24360979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.11.001
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