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Glycation Cross-Linking Induced Mechanical-Enzymatic Cleavage of Microscale Tendon Fibers

Recent molecular modeling data using collagen peptides predicted that mechanical force transmitted through intermolecular cross-links resulted in collagen triple helix unwinding. These simulations further predicted that this unwinding, referred to as triple helical microunfolding, occurred at forces...

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Detalhes bibliográficos
Main Authors: Bourne, Jonathan W., Lippell, Jared M., Torzilli, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019702/
https://ncbi.nlm.nih.gov/pubmed/24316373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.11.005
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