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A Note on Exact Differences between Beta Distributions in Genomic (Methylation) Studies

We apply a known algorithm for computing exactly inequalities between Beta distributions to assess whether a given position in a genome is differentially methylated across samples. We discuss the advantages brought by the adoption of this solution with respect to two approximations (Fisher's te...

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Detalhes bibliográficos
Main Authors: Raineri, Emanuele, Dabad, Marc, Heath, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019606/
https://ncbi.nlm.nih.gov/pubmed/24824426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097349
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