Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase.

Protein kinase C (PKC), a major cellular receptor for tumor-promoting phorbol esters and diacylglycerols (DGs), appears to be involved in a variety of cellular functions, although its activation mechanism in vivo is not yet fully understood. To evaluate the signaling pathways involved in the activat...

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Bibliografiske detaljer
Main Authors: Moriya, S, Kazlauskas, A, Akimoto, K, Hirai, S, Mizuno, K, Takenawa, T, Fukui, Y, Watanabe, Y, Ozaki, S, Ohno, S
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC40196/
https://ncbi.nlm.nih.gov/pubmed/8552594
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