Polymorphisms of uridine glucuronosyltransferase gene and irinotecan toxicity: low dose does not protect from toxicity

Uridine glucuronosyltransferase (UGT) gene polymorphisms have been linked to irinotecan toxicity. Our purpose was to study the association between UGT1A1*28, UGT1A7*2, and UGT1A7*3 polymorphisms and irinotecan toxicity in Greek patients receiving low-dose weekly irinotecan. Blood samples were collec...

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Autors principals: Tziotou, Marianna, Kalotychou, Vassiliki, Ntokou, Anna, Tzanetea, Revekka, Armenis, Iakovos, Varsou, Marianna, Konstantopoulos, Konstantinos, Tsavaris, Nicolas, Rombos, Yannis
Format: Artigo
Idioma:Inglês
Publicat: Cancer Intelligence 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019457/
https://ncbi.nlm.nih.gov/pubmed/24834123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3332/ecancer.2014.428
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