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Trifluoromethylation of Heterocycles in Water at Room Temperature

Using a reaction medium containing nanoparticles consisting of commercially available TPGS-750-M in water, a combination of Langlois’ reagent and t-BuOOH can be used to effect trifluoromethylation of several heterocyclic arrays, including heteroaromatics. These reactions take place at ambient temper...

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Detalhes bibliográficos
Main Authors: Fennewald, James C., Lipshutz, Bruce H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019426/
https://ncbi.nlm.nih.gov/pubmed/24839397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3GC42119H
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