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Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alum

Vaccination against nicotine is a potential treatment for tobacco smoking. Clinical trials show effect only in high antibody responders; therefore it is necessary to increase the effectiveness of nicotine vaccines. The use of a multivalent vaccine that activates several B cell populations is a possi...

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Detalhes bibliográficos
Main Authors: de Villiers, Sabina H.L., Cornish, Katherine E., Troska, Andrew J., Pravetoni, Marco, Pentel, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019346/
https://ncbi.nlm.nih.gov/pubmed/24176492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.10.051
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