Clostridium difficile Extracytoplasmic Function σ Factor σ(V) Regulates Lysozyme Resistance and Is Necessary for Pathogenesis in the Hamster Model of Infection

Clostridium difficile is a clinically important pathogen and the most common cause of hospital-acquired infectious diarrhea. Expression of the C. difficile gene csfV, which encodes σ(V), an extracytoplasmic function σ factor, is induced by lysozyme, which damages the peptidoglycan of bacteria. Here...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ho, Theresa D., Williams, Kyle B., Chen, Yan, Helm, Richard F., Popham, David L., Ellermeier, Craig D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019185/
https://ncbi.nlm.nih.gov/pubmed/24664503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01483-13
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires