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Clostridium difficile Extracytoplasmic Function σ Factor σ(V) Regulates Lysozyme Resistance and Is Necessary for Pathogenesis in the Hamster Model of Infection
Clostridium difficile is a clinically important pathogen and the most common cause of hospital-acquired infectious diarrhea. Expression of the C. difficile gene csfV, which encodes σ(V), an extracytoplasmic function σ factor, is induced by lysozyme, which damages the peptidoglycan of bacteria. Here...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019185/ https://ncbi.nlm.nih.gov/pubmed/24664503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01483-13 |
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