Aerobactin Mediates Virulence and Accounts for Increased Siderophore Production under Iron-Limiting Conditions by Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae

Hypervirulent (hypermucoviscous) Klebsiella pneumoniae (hvKP) strains are an emerging variant of “classical” K. pneumoniae (cKP) that cause organ and life-threatening infection in healthy individuals. An understanding of hvKP-specific virulence mechanisms that enabled evolution from cKP is limited....

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Autors principals: Russo, Thomas A., Olson, Ruth, MacDonald, Ulrike, Metzger, Daniel, Maltese, Lauren M., Drake, Eric J., Gulick, Andrew M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019165/
https://ncbi.nlm.nih.gov/pubmed/24664504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01667-13
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