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In Vivo Splenic Clearance Correlates with In Vitro Deformability of Red Blood Cells from Plasmodium yoelii-Infected Mice

Recent experimental and clinical studies suggest a crucial role of mechanical splenic filtration in the host's defense against malaria parasites. Subtle changes in red blood cell (RBC) deformability, caused by infection or drug treatment, could influence the pathophysiological outcome. However,...

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Detalhes bibliográficos
Main Authors: Huang, Sha, Amaladoss, Anburaj, Liu, Min, Chen, Huichao, Zhang, Rou, Preiser, Peter R., Dao, Ming, Han, Jongyoon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019160/
https://ncbi.nlm.nih.gov/pubmed/24686065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01525-13
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