Yeast Virus-Derived Stimulator of the Innate Immune System Augments the Efficacy of Virus Vector-Based Immunotherapy

To identify novel stimulators of the innate immune system, we constructed a panel of eight HEK293 cell lines double positive for human Toll-like receptors (TLRs) and an NF-κB-inducible reporter gene. Screening of a large variety of compounds and cellular extracts detected a TLR3-activating compound...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Claudepierre, Marie-Christine, Hortelano, Julie, Schaedler, Emmanuelle, Kleinpeter, Patricia, Geist, Michel, Remy-Ziller, Christelle, Brandely, Renée, Tosch, Caroline, Laruelle, Laurence, Jawhari, Anass, Menguy, Thierry, Marchand, Jean-Baptiste, Romby, Pascale, Schultz, Patrick, Hartmann, Gunther, Rooke, Ronald, Bonnefoy, Jean-Yves, Preville, Xavier, Rittner, Karola
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Vaccines and Antiviral Agents
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019141/
https://ncbi.nlm.nih.gov/pubmed/24574403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03819-13
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