Complementary Induction of Immunogenic Cell Death by Oncolytic Parvovirus H-1PV and Gemcitabine in Pancreatic Cancer

Novel therapies employing oncolytic viruses have emerged as promising anticancer modalities. The cure of particularly aggressive malignancies requires induction of immunogenic cell death (ICD), coupling oncolysis with immune responses via calreticulin, ATP, and high-mobility group box protein B1 (HM...

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Hauptverfasser: Angelova, Assia L., Grekova, Svitlana P., Heller, Anette, Kuhlmann, Olga, Soyka, Esther, Giese, Thomas, Aprahamian, Marc, Bour, Gaétan, Rüffer, Sven, Cziepluch, Celina, Daeffler, Laurent, Rommelaere, Jean, Werner, Jens, Raykov, Zahari, Giese, Nathalia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019131/
https://ncbi.nlm.nih.gov/pubmed/24574398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03688-13
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