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Comparison of Varicella-Zoster Virus RNA Sequences in Human Neurons and Fibroblasts

Varicella-zoster virus (VZV) infection causes varicella, after which the virus becomes latent in ganglionic neurons. In tissue culture, VZV-infected human neurons remain viable at 2 weeks, whereas fibroblasts develop cytopathology. Next-generation RNA sequencing was used to compare VZV transcriptome...

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Detalhes bibliográficos
Main Authors: Baird, Nicholas L., Bowlin, Jacqueline L., Cohrs, Randall J., Gilden, Don, Jones, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019124/
https://ncbi.nlm.nih.gov/pubmed/24600007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00476-14
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