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A Temporospatial Map That Defines Specific Steps at Which Critical Surfaces in the Gag MA and CA Domains Act during Immature HIV-1 Capsid Assembly in Cells

During HIV-1 assembly, Gag polypeptides target to the plasma membrane, where they multimerize to form immature capsids that undergo budding and maturation. Previous mutational analyses identified residues within the Gag matrix (MA) and capsid (CA) domains that are required for immature capsid assemb...

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Bibliografske podrobnosti
Main Authors: Robinson, Bridget A., Reed, Jonathan C., Geary, Clair D., Swain, J. Victor, Lingappa, Jaisri R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019110/
https://ncbi.nlm.nih.gov/pubmed/24623418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03609-13
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