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Clinical Targeting of Mutated and Wild-Type Protein Tyrosine Kinases in Cancer

Clinical therapies for cancer have evolved from toxic, nontargeted agents to manageable, highly targeted therapies. Protein tyrosine kinases are a family of signaling molecules implicated in nearly every cancer type and are the foundation for the development of modern targeted agents. Recent genomic...

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Bibliografiske detaljer
Main Authors: Drake, Justin M., Lee, John K., Witte, Owen N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019040/
https://ncbi.nlm.nih.gov/pubmed/24567371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01592-13
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