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Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle

Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8(+) cytotoxic T lymphocytes (CTL). Here, we report on the generation of seven recombinant bovine leukocyte antigens (BoLA) and recom...

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Autors principals: Svitek, Nicholas, Hansen, Andreas Martin, Steinaa, Lucilla, Saya, Rosemary, Awino, Elias, Nielsen, Morten, Buus, Søren, Nene, Vishvanath
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018993/
https://ncbi.nlm.nih.gov/pubmed/24775445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-45-50
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