Development and Use of a Serum Bactericidal Assay Using Pooled Human Complement To Assess Responses to a Meningococcal Group A Conjugate Vaccine in African Toddlers

A meningococcal group A polysaccharide (PS) conjugate vaccine (PsA-TT) has been developed for African countries affected by epidemic meningitis caused by Neisseria meningitidis. Complement-mediated serum bactericidal antibody (SBA) assays are used to assess protective immune responses to meningococc...

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Detalhes bibliográficos
Main Authors: Bash, Margaret C., Lynn, Freyja, Mocca, Brian, Borrow, Ray, Findlow, Helen, Hassan-King, Musa, Preziosi, Marie-Pierre, Idoko, Olubukola, Sow, Samba, Kulkarni, Prasad, LaForce, F. Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018891/
https://ncbi.nlm.nih.gov/pubmed/24671551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00812-13
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