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Direct Neutralization of Type III Effector Translocation by the Variable Region of a Monoclonal Antibody to Yersinia pestis LcrV

Plague is an acute infection caused by the Gram-negative bacterium Yersinia pestis. Antibodies that are protective against plague target LcrV, an essential virulence protein and component of a type III secretion system of Y. pestis. Secreted LcrV localizes to the tips of type III needles on the bact...

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Detalhes bibliográficos
Main Authors: Ivanov, Maya I., Hill, Jim, Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018875/
https://ncbi.nlm.nih.gov/pubmed/24599533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00013-14
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