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Structurally diverse low molecular weight activators of the mammalian pre-mRNA 3′ cleavage reaction

The 3′ end formation of mammalian pre-mRNA contributes to gene expression regulation by setting the downstream boundary of the 3′ untranslated region, which in many genes carries regulatory sequences. A large number of protein cleavage factors participate in this pre-mRNA processing step, but chemic...

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Autors principals: Liu, Min Ting, Nagre, Nagaraja N., Ryan, Kevin
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018835/
https://ncbi.nlm.nih.gov/pubmed/24373842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.12.006
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