Functional promoter -765 G > C variant in COX-2 gene is associated with the susceptibility of breast cancer in Chinese Han women

BACKGROUND: Cyclooxygenase (COX) is a rate-limiting enzyme in prostaglandins synthesis which exists in two isoforms, COX-1 and COX-2. Over-expression of COX-2 was considered to increase the proliferation and enhance the invasiveness of breast cancer cells. It was suggested that genetic variations in...

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Библиографические подробности
Главные авторы: Gao, Jie, Kang, Hua-Feng, Ma, Xiao-Bin, Tang, Wei, Liu, Di, Zhao, Yang, Zhang, Shu-Qun, Guan, Hai-Tao, Lin, Shuai, Ren, Hong-Tao, Wang, Xi-Jing, Dai, Zhi-Jun
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Primary Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018614/
https://ncbi.nlm.nih.gov/pubmed/24826080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-38
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