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The Challenges of Decision-making Regarding Futility in a Randomized Trial: the IMS III Experience

BACKGROUND AND PURPOSE: IMS III is a randomized, parallel arm trial comparing the approach of IV t-PA followed by endovascular treatment (“endovascular”) with IV t-PA alone in patients with acute ischemic stroke presenting within three hours of symptom onset. The trial intended to enroll 900 subject...

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Detalhes bibliográficos
Main Authors: Yeatts, Sharon D, Martin, Renee’ H, Coffey, Christopher S, Lyden, Patrick D, Foster, Lydia D, Woolson, Robert F, Broderick, Joseph P, Di Tullio, Marco R., Jungreis, Charles A, Palesch, Yuko Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018452/
https://ncbi.nlm.nih.gov/pubmed/24699059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.003925
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