Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice

Several reports indicate that melatonin alleviates bleomycin (BLM)-induced pulmonary fibrosis in rodent animals. Nevertheless, the exact mechanism remains obscure. The present study investigated the effects of melatonin on endoplasmic reticulum (ER) stress and epithelial-mesenchymal transition (EMT)...

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Hlavní autoři: Zhao, Hui, Wu, Qing-Qing, Cao, Lin-Feng, Qing, Hou-Ying, Zhang, Cheng, Chen, Yuan-Hua, Wang, Hua, Liu, Rong-Ru, Xu, De-Xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018327/
https://ncbi.nlm.nih.gov/pubmed/24818755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097266
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