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Development and Characterization of an Antibody-Labeled Super-Paramagnetic Iron Oxide Contrast Agent Targeting Prostate Cancer Cells for Magnetic Resonance Imaging

In this study we developed, characterized and validated in vitro a functional superparagmagnetic iron-oxide based magnetic resonance contrast agent by conjugating a commercially available iron oxide nanoparticle, Molday ION Rhodamine-B Carboxyl (MIRB), with a deimmunized mouse monoclonal antibody (m...

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Detalhes bibliográficos
Main Authors: Bates, David, Abraham, Suraj, Campbell, Michael, Zehbe, Ingeborg, Curiel, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018298/
https://ncbi.nlm.nih.gov/pubmed/24819929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097220
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