APOE associations with severe CAA-associated vasculopathic changes – collaborative meta-analysis

OBJECTIVES: Cerebral amyloid angiopathy (CAA) is associated with lobar intracerebral haemorrhage (ICH). While only the ε4 allele of the apolipoprotein E gene (APOE) is associated with the presence of CAA, both APOE-ε4 and ε2 are associated with lobar ICH. The generally accepted explanation is that A...

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Autori principali: Rannikmäe, Kristiina, Kalaria, Rajesh N, Greenberg, Steven M, Chui, Helena C, Schmitt, Frederick A, Samarasekera, Neshika, Salman, Rustam Al-Shahi, Sudlow, Cathie LM
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018226/
https://ncbi.nlm.nih.gov/pubmed/24163429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2013-306485
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