The 4G/4G Genotype of the PAI-1 (Serpine-1) 4G/5G Polymorphism Is Associated With Decreased Lung Allograft Utilization

Widespread thrombi are found among donor lungs rejected for transplantation. The 4G/5G polymorphism in the plasminogen activator inhibitor (PAI-1) gene impacts transcription and the 4G allele is associated with increased PAI-1 levels. We hypothesized that the 4G/4G genotype would be associated with...

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Main Authors: Sapru, A., Zaroff, J. G., Pawlikowska, L., Liu, K. D., Khush, K. K., Baxter-Lowe, L. A., Hayden, V., Menza, R. L., Convery, M., Lo, V., Poon, A., Kim, H., Young, W. L., Kukreja, J., Matthay, M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018219/
https://ncbi.nlm.nih.gov/pubmed/22390401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.03996.x
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