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Extracting SAR Information from a Large Collection of Anti-Malarial Screening Hits by NSG-SPT Analysis

[Image: see text] We combine two graphical SAR analysis methods, Network-like Similarity Graphs (NSGs) and Similarity-Potency Trees (SPTs), to search for SAR information in a large and heterogeneous compound data set containing more than 13,000 antimalarial screening hits that was recently released...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wawer, Mathias, Bajorath, Jürgen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2011
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018131/
https://ncbi.nlm.nih.gov/pubmed/24900303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100240z
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