Automated Lead Optimization of MMP-12 Inhibitors Using a Genetic Algorithm

[Image: see text] Traditional lead optimization projects involve long synthesis and testing cycles, favoring extensive structure−activity relationship (SAR) analysis and molecular design steps, in an attempt to limit the number of cycles that a project must run to optimize a development candidate. M...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pickett, Stephen D., Green, Darren V. S., Hunt, David L., Pardoe, David A., Hughes, Ian
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2010
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018106/
https://ncbi.nlm.nih.gov/pubmed/24900251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100191f
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker