Targeting Anthracycline-Resistant Tumor Cells with Synthetic Aloe-Emodin Glycosides

[Image: see text] The cytotoxic activity of aloe-emodin (AE), a natural anthranoid that readily permeates anthracycline-resistant tumor cells, was improved by the attachment of an amino-sugar unit to its anthraquinone core. The new class of AE glycosides (AEGs) showed a significant improvement in cy...

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Autors principals: Breiner-Goldstein, Elinor, Evron, Zoharia, Frenkel, Michael, Cohen, Keren, Meiron, Keren Nir, Peer, Dan, Roichman, Yael, Flescher, Eliezer, Fridman, Micha
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2011
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018067/
https://ncbi.nlm.nih.gov/pubmed/24900344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2001104
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