Genetic variation in the beta-2 adrenergic receptor (ADRB2) predicts functional gastrointestinal diagnoses and poorer health-related quality of life

BACKGROUND: The beta-2 adrenergic receptor (ADRB2) is an important target for epinephrine, a neurotransmitter in pain signalling. ADRB2 haplotypes affect receptor expression and ligand response, and have been linked to painful non-GI disorders. AIMS: To assess whether ADRB2 polymorphisms (rs1042713,...

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Main Authors: Kushnir, V. M., Cassell, B., Gyawali, C. P., Newberry, R. D., Kibe, P., Nix, B. D., Sabzpoushan, A., Kanuri, N. D., Sayuk, G. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017784/
https://ncbi.nlm.nih.gov/pubmed/23786226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.12378
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