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The Pou5f1 distal enhancer is sufficient to drive Pou5f1 promoter-EGFP expression in embryonic stem cells

The POU5F1 transcription factor is the gatekeeper of the pluripotent state in mammals. It is essential for epigenetic reprogramming events and also for germ cell viability. The Pou5f1 gene’s expression is tightly controlled during embryogenesis, but its regulatory regions are not fully deciphered. T...

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Autori principali: Liao, Ji, He, Yikun, Szabó, Piroska E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017653/
https://ncbi.nlm.nih.gov/pubmed/24395560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1387/ijdb.120186ps
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