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(2S,4R)-4-Hydroxyproline(4-nitrobenzoate): Strong Induction of Stereoelectronic Effects via a Readily Synthesized Proline Derivative. Crystallographic Observation of a Correlation between Torsion Angle and Bond Length in a Hyperconjugative Interaction

[Image: see text] (2S,4R)-4-Hydroxyproline(4-nitrobenzoate) was synthesized. The crystal structure revealed an exo ring pucker, with the nitrobenzoate pseudoaxial on the pyrrolidine envelope and antiperiplanar to C(β) and C(δ) C–H bonds. The unit cell exhibited variation in C(δ)–H/C(γ)–O and C(β)–H/...

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Autors principals: Pandey, Anil K., Yap, Glenn P. A., Zondlo, Neal J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017608/
https://ncbi.nlm.nih.gov/pubmed/24720652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500367d
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