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Secondary Structure in the Core of Amyloid Fibrils Formed from Human β(2)m and its Truncated Variant ΔN6

[Image: see text] Amyloid fibrils formed from initially soluble proteins with diverse sequences are associated with an array of human diseases. In the human disorder, dialysis-related amyloidosis (DRA), fibrils contain two major constituents, full-length human β(2)-microglobulin (hβ(2)m) and a trunc...

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Detalhes bibliográficos
Main Authors: Su, Yongchao, Sarell, Claire J., Eddy, Matthew T., Debelouchina, Galia T., Andreas, Loren B., Pashley, Clare L., Radford, Sheena E., Griffin, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017606/
https://ncbi.nlm.nih.gov/pubmed/24679070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4126092
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