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Vav1 is Essential for Mechanotactic Crawling and Migration of Neutrophils out of the Inflamed Microvasculature

Mac-1 dependent crawling is a new step in the leukocyte recruitment cascade which follows LFA-1 dependent adhesion and precedes emigration. Neutrophil adhesion via LFA-1 has been shown to induce cytoskeletal reorganization through Vav1-dependent signaling, and the current study investigates the role...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Phillipson, Mia, Heit, Bryan, Parsons, Sean A., Petri, Björn, Mullaly, Sarah C., Colarusso, Pina, Gower, R. Michael, Neely, Gregory, Simon, Scott I., Kubes, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017595/
https://ncbi.nlm.nih.gov/pubmed/19454683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803414
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