Inhibiting the oncogenic mir-221 by microRNA sponge: toward microRNA-based therapeutics for hepatocellular carcinoma

AIM: We evaluated the capability of “microRNA sponges” in sequestering and inhibiting the over-expressed miR-221 in HCC cell lines. BACKGROUND: Advanced hepatocellular carcinoma (HCC) is a serious public health problem, with no effective cure at present. It has been demonstrated that the deregulatio...

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Bibliographic Details
Main Authors: Moshiri, Farzaneh, Callegari, Elisa, D'Abundo, Lucilla, Corrà, Fabio, Lupini, Laura, Sabbioni, Silvia, Negrini, Massimo
Format: Artigo
Language:Inglês
Published: Research Institute for Gastroenterology and Liver Diseases 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017557/
https://ncbi.nlm.nih.gov/pubmed/25436097
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