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Green Tea Polyphenol Epigallocatechin 3-Gallate, Contributes to the Degradation of DNMT3A and HDAC3 in HCT 116 Human Colon Cancer Cells

BACKGROUND: Colon cancer is still the second leading cause of cancer deaths in the United States. Epigenetic gene silencing involving DNA methyltransferases (DNMTs) and histone deacetylases (HDACs) play an important role in the progression of colon cancer. MATERIALS AND METHODS: Here we found that t...

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Detalhes bibliográficos
Main Authors: MOSELEY, VONDINA R., MORRIS, JAY, KNACKSTEDT, REBECCA W., WARGOVICH, MICHAEL J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017340/
https://ncbi.nlm.nih.gov/pubmed/24324066
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