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Functions and Regulation of the APOBEC Family of Proteins

APOBEC1 is a cytidine deaminase that edits messenger RNAs and was the first enzyme in the APOBEC family to be functionally characterized. Under appropriate conditions APOBEC1 also deaminates deoxycytidine in single-stranded DNA (ssDNA). The other ten members of the APOBEC family have not been fully...

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Bibliographic Details
Main Authors: Smith, Harold C., Bennett, Ryan P., Kizilyer, Ayse, McDougall, William M., Prohaska, Kimberly M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017262/
https://ncbi.nlm.nih.gov/pubmed/22001110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.10.004
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