An Autism Spectrum Disorder Susceptibility Gene, TAO2, is Important for Basal Dendrite Formation in the Neocortex

How neurons develop their morphology is an important question in neurobiology. Here we describe a novel pathway that specifically affects the formation of basal dendrites and axonal projections in cortical pyramidal neurons. We report that thousand-and-one-amino acid 2 (TAO2) kinase plays an essenti...

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Detalhes bibliográficos
Main Authors: de Anda, Froylan Calderon, Rosario, Ana Lucia, Durak, Omer, Tran, Tracy, Gräff, Johannes, Meletis, Konstantinos, Rei, Damien, Soda, Takahiro, Madabhushi, Ram, Ginty, David D., Kolodkin, Alex L., Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017029/
https://ncbi.nlm.nih.gov/pubmed/22683681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3141
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