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Effect of Curcumin on Lifespan, Activity Pattern, Oxidative Stress, and Apoptosis in the Brains of Transgenic Drosophila Model of Parkinson's Disease

Background. A time dependent loss of dopaminergic neurons and the formation of intracellular aggregates of alpha synuclein have been reported in PD model flies. Methods. The progeny (PD flies) expressing human alpha synuclein was exposed to 25, 50, and 100 µM of curcumin mixed in the diet for 24 day...

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Autors principals: Siddique, Yasir Hasan, Naz, Falaq, Jyoti, Smita
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016861/
https://ncbi.nlm.nih.gov/pubmed/24860828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/606928
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