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Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Wen-Dan Decoction (WDD), a formula of traditional Chinese medicine, has been clinically used for treating insomnia for approximately 800 years. However, the therapeutic mechanisms of WDD remain unclear. Orexin-A plays a key role in the sleep-wake cycle, while leptin function is opposite to orexin-A....

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Detalhes bibliográficos
Main Authors: Wu, Fengzhi, Song, Yuehan, Li, Feng, He, Xin, Ma, Jie, Feng, Ting, Guan, Binghe, Wang, Liye, Li, Sinai, Liu, Xiaolan, Liu, Yan, Mao, Meng, Liu, Jing, Bai, Shijing, Song, Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016855/
https://ncbi.nlm.nih.gov/pubmed/24864160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/872547
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