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FOXO Transcription Factors: Their Clinical Significance and Regulation

Members of the class O of forkhead box transcription factors (FOXO) have important roles in metabolism, cellular proliferation, stress resistance, and apoptosis. The activity of FOXOs is tightly regulated by posttranslational modification, including phosphorylation, acetylation, and ubiquitylation....

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Hlavní autoři: Wang, Yu, Zhou, Yanmin, Graves, Dana T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016844/
https://ncbi.nlm.nih.gov/pubmed/24864265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/925350
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