Rectal Mucosal Quantitative Galactose Oxidase-Schiff Reaction as an Early Detection Biomarker for Colorectal Cancer: Comparison to Fecal Occult Stool Blood Test

The galactose oxidase-Schiff (GOS) reaction detects D-galactose-β-[1,3]-N-acetyl-D-galactosamine. This is a T-antigen expressed in mucus from malignant cells and colonic mucosa adjacent to cancer but not in normal mucosa. Previous studies using a qualitative GOS assay proved to be of limited value f...

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Main Authors: Ruffin, Mack T., Normolle, Daniel P., Evelegh, Michael J., Baron, John A., Bresalier, Robert S., Marcon, Norman E., Syngal, Sapna, Turgeon, D. Kim, Tuck, Melissa K., Brenner, Dean E.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016824/
https://ncbi.nlm.nih.gov/pubmed/21896998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CBM-2011-0206
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