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The crucial role of mechanical heterogeneity in regulating follicle development and ovulation with engineered ovarian microtissue

Contemporary systems for in vitro culture of ovarian follicles do not recapitulate the mechanical heterogeneity in mammalian ovary. Here we report microfluidic generation of biomimetic ovarian microtissue for miniaturized three-dimensional (3D) culture of early secondary preantral follicles by using...

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Detalhes bibliográficos
Main Authors: Choi, Jung Kyu, Agarwal, Pranay, Huang, Haishui, Zhao, Shuting, He, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016819/
https://ncbi.nlm.nih.gov/pubmed/24702961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.03.028
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