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The crucial role of mechanical heterogeneity in regulating follicle development and ovulation with engineered ovarian microtissue

Contemporary systems for in vitro culture of ovarian follicles do not recapitulate the mechanical heterogeneity in mammalian ovary. Here we report microfluidic generation of biomimetic ovarian microtissue for miniaturized three-dimensional (3D) culture of early secondary preantral follicles by using...

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Bibliografiske detaljer
Main Authors: Choi, Jung Kyu, Agarwal, Pranay, Huang, Haishui, Zhao, Shuting, He, Xiaoming
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016819/
https://ncbi.nlm.nih.gov/pubmed/24702961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.03.028
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